BDBM50606681 CHEMBL5219846

SMILES OC(=O)CNC(=O)c1nc(Nc2ccc(cc2)[N+]([O-])=O)ccc1O

InChI Key InChIKey=ITMKUXMZMOBJES-UHFFFAOYSA-N

Data  9 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50606681   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50606681(CHEMBL5219846)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO demethylation activity expressed in Escherichia coli BL21 (DE3) incub...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50606681(CHEMBL5219846)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 (DE3) incubated for 10 mins using ...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50606681(CHEMBL5219846)
Affinity DataKd:  340nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair